Advertisement

An experimental characterization of ventilation motions in healthy subjects

      Highlights

      • Numerical evaluation of the biomechanics of ventilation
      • Using a specifically developed device
      • Motion parameters of a rib during ventilation test
      • Statistical interpretations from a campaign of tests.

      Abstract

      Background: Existing devices detect main breathing data and none is aimed to monitor biomechanics of ventilation motions with small wearable device.
      Methods: The used device has been designed for noninvasive wearing to detect main motion parameters of a rib during ventilation in an experimental campaign with 218 subjects. Experimental activity is carried out by testing in vivo with human volunteers for an experimental characterization of ventilation motions as related to normal breathing, maximal breathing and coughing.
      Findings: Findings can be summarized from a numerical analysis of experimental results in terms of statistical values of ventilation motion parameters in rotation and acceleration as function of age and sex of the tested subjects. The discussed campaign reporting results on healthy patients was carried out with the aim to build a reference database of normal conditions against which the status of patients with both thoracic and ventilation problems can then be judged. Females showed significantly larger lateral-to-lateral movements during basal breathing and lateral-to-lateral Z-axis movements during maximal breathing and cough. Males demonstrated wider antero-posterior Y-axis and cranio-caudal X-axis movements during maximal breathing, while antero-posterior movements prevailed during cough. Older participants demonstrated larger lateral-to-lateral Z-axis and antero-posterior Y-axis movements during basal breathing. Young participants showed more significant increments along antero-posterior Y-axis from basal to maximal breathing and basal to cough, demonstrating a more efficient muscular activity.
      Interpretation: The ventilation motion during ventilation act is useful to detect the status of ventilation and can give indications for diagnostics and medical solutions even in thoracic surgery.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Clinical Biomechanics
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Ambrogi V.
        • Ceccarelli M.
        Fixing plate for ostyeosynthesis of fractured ribs, Patent no. IT. 102019000005638, Italy.
        2021
        • Ceccarelli M.
        Portable Device for Measuring the Movement of Human Ribs, Patent.
        (n. IT102021000005726, 19-4-2019)2019: 13 (Italy)
        • Ceccarelli M.
        • Aguilar Perez L.A.
        • Torres San-Miguel C.R.
        Testing machine for artificial ribs, Patent no. IT. 102017000036498, Italy.
        2019
        • De Groote A.
        • Wantier M.
        • Cheron G.
        • Estenne M.
        • Paiva M.
        Chest wall motion during tidal breathing.
        J. Appl. Physiol. 1997; 83: 1531-1537https://doi.org/10.1152/jappl.1997.83.5.1531
        • Derenne J.-P.
        • Macklem P.T.
        • Roussos C.
        State of the art. The respiratory muscles: mechanics, control and pathophysiology. Part I.
        Am. Rev. Respir. Dis. 1978; 118: 119-133
        • Goldman M.D.
        • Mead J.
        Mechanical interaction between the diaphragm and rib cage.
        J. Appl. Physiol. 1973; 35: 197-204
        • Grassino A.
        • Goldman M.D.
        • Mead J.
        Sears TA (1978) mechanics of the human diaphragm during voluntary contraction: statics.
        J Appl Physiol: Respir Envir Exercise Physiol. 1978; 44: 829-839
        • Gray's Anatomy
        Paperbook, The Anatomical Basis of Clinical Practice.
        Elsevier, 2020
        • Guyton A.
        • Halls J.
        Textbook of Medical Physiology.
        WB Saunders Company, 1995
        • Haines K.L.
        • Agarwal S.
        Postoperative pulmonary complications-a multifactorial outcome.
        JAMA Surg. 2017; 152 (PMID: 27829075): 166-167https://doi.org/10.1001/jamasurg.2016.4102
        • Hussain A.
        • Burns B.
        Anatomy, Thorax, Wall. 2020 Jul 31. In: StatPearls [Internet].
        StatPearls Publishing, Treasure Island (FL)2020
        • Lo Mauro A.
        • Aliverti A.
        Sex differences in respiratory function.
        Breathe (Sheff). 2018; 14: 131-140https://doi.org/10.1183/20734735.000318
        • Luu B.L.
        • McDonald R.J.
        • Bolsterlee B.
        • Héroux M.E.
        • Butler J.E.
        • Hudson A.L.
        Movement of the ribs in supine humans for small and large changes in lung volume.
        J Appl Physiol. 2021; 131: 174-183https://doi.org/10.1152/japplphysiol.01046.2020
        • Macklem P.T.
        Normal and abnormal function of the diaphragm.
        Thorax. 1981; 36: 161-163
        • Macklem P.T.
        • Gross D.
        • Grassino A.
        • Roussos C.
        Partitioning of inspiratory pressure swings between diaphragm and intercostal/accessory muscles.
        J Appl Physiol: Respir Envir Exercise Physiol. 1978; 44: 200-208
        • Primiano Jr., F.P.
        Theoretical analysis of chest wall mechanics.
        J. Biomech. 1982; 15: 919-931https://doi.org/10.1016/0021-9290(82)90010-0
        • Ross B.B.
        • Gramiak R.
        • Rahn H.
        Physical dynamics of the cough mechanism.
        J. Appl. Physiol. 1955; 8: 264-268
        • Sommariva L.
        • Luis Arreguin J.
        • Morales C.
        • Ceccarelli M.
        • Ambrogi V.
        • Puglisi L.
        Design and lab experiences for a fixator of rib fractures, new trends in medical and service robotics - MESROB 2021, springer nature Switzerland AG 2021.
        MMS. 2021; 93: 1-9https://doi.org/10.1007/978-3-030-58104-6_18
        • Wilson T.A.
        • Rehder K.
        • Krayer S.
        • Hoffman E.A.
        • Whitney C.G.
        • Rodarte J.R.
        Geometry and respiratory displacement of human ribs.
        J. Appl. Physiol. 1985; 62 (PMID: 3597261): 1872-1877https://doi.org/10.1152/jappl.1987.62.5.1872